RESUMO
Syringocystadenoma papilliferum is a rare, benign adnexal tumor of eccrine or apocrine origin that typically presents at birth or before puberty. Syringocystadenoma papilliferum is associated with a nevus sebaceus in about 40% of cases. We present a 50-year old woman with a pink-orange plaque and nodule on the scalp, consistent with syringocystadenoma papilliferum that arose within a nevus sebaceus.
Assuntos
Dermatoses do Couro Cabeludo/patologia , Neoplasias das Glândulas Sudoríparas/patologia , Adenomas Tubulares de Glândulas Sudoríparas/patologia , Biópsia , Feminino , Humanos , Pessoa de Meia-Idade , Dermatoses do Couro Cabeludo/cirurgia , Neoplasias das Glândulas Sudoríparas/cirurgia , Adenomas Tubulares de Glândulas Sudoríparas/cirurgiaRESUMO
BACKGROUND: Hidradenoma papilliferum is a rare benign neoplasm arising from apocrine glands. It occurs commonly on the anogenital region of middle-aged women. It usually presents as a slow growing, solitary asymptomatic, skin colored or red nodule less than 1 cm in diameter. CASE PRESENTATION: The case is a 38-year-old, white woman who presented with a painful nodule occurring within a month in the himenal region of the posterior vaginal introitus. The nodule was excisied and the histology revealed a hidradenoma papilliferum. The diagnosis and treatment of hidradenoma papilliferum is possible with surgical removal and histopathological evaluation of nodules. CONCLUSION: When an adult woman presents with a noduler lesion in the anogenital area, sexually transmitted diseases and other benign and malignant vulvar lesions, as well as malignant transformation is very rare but,should be kept in mind; however because it has been reported and long-term clinical follow-up is suggested.
Assuntos
Neoplasias das Glândulas Sudoríparas , Adenomas Tubulares de Glândulas Sudoríparas , Adulto , Feminino , Humanos , Hímen , Pessoa de Meia-Idade , Períneo , Neoplasias das Glândulas Sudoríparas/diagnóstico , Neoplasias das Glândulas Sudoríparas/cirurgia , Adenomas Tubulares de Glândulas Sudoríparas/cirurgia , VulvaRESUMO
Hidradenoma papilliferum (HP) is a rare, slow-growing, benign adnexal tumour with apocrine differentiation. It usually affects the anogenital region in adult women and is clinically polymorphous, mimicking other benign or malignant neoformations. The dermoscopic features of vulval HP have not been reported yet. We report the clinical and dermoscopic features in a case series of histopathologically proven vulval HPs. Dermoscopy may be a useful tool for the diagnosis of vulval HP. To our knowledge, our paper represents the first report of dermoscopic findings in a series of vulval HPs in a multiracial population.
Assuntos
Dermoscopia/métodos , Couro Cabeludo/patologia , Neoplasias das Glândulas Sudoríparas/patologia , Adenomas Tubulares de Glândulas Sudoríparas/diagnóstico , Neoplasias Vulvares/patologia , Adulto , Idoso , Carcinoma de Células Escamosas/diagnóstico , Carcinoma de Células Escamosas/patologia , Coristoma/diagnóstico , Coristoma/epidemiologia , Coristoma/patologia , Dermoscopia/estatística & dados numéricos , Diagnóstico Diferencial , Porocarcinoma Écrino/diagnóstico , Porocarcinoma Écrino/patologia , Feminino , Humanos , Índia/epidemiologia , Itália/epidemiologia , Masculino , Pessoa de Meia-Idade , Doença de Paget Extramamária/diagnóstico , Doença de Paget Extramamária/patologia , Estudos Retrospectivos , Adenomas Tubulares de Glândulas Sudoríparas/etnologia , Adenomas Tubulares de Glândulas Sudoríparas/cirurgiaRESUMO
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Assuntos
Humanos , Masculino , Adulto , Adenomas Tubulares de Glândulas Sudoríparas/diagnóstico , Adenomas Tubulares de Glândulas Sudoríparas/cirurgia , Eletrocoagulação/métodos , Adenomas Tubulares de Glândulas Sudoríparas/patologia , Escápula/patologia , Hiperceratose Epidermolítica/patologia , Diagnóstico Diferencial , Biópsia , Adenomas Tubulares de Glândulas Sudoríparas/congênitoAssuntos
Neoplasias das Glândulas Sudoríparas/congênito , Adenomas Tubulares de Glândulas Sudoríparas/congênito , Diagnóstico Diferencial , Humanos , Masculino , Escápula , Neoplasias das Glândulas Sudoríparas/patologia , Neoplasias das Glândulas Sudoríparas/cirurgia , Adenomas Tubulares de Glândulas Sudoríparas/patologia , Adenomas Tubulares de Glândulas Sudoríparas/cirurgia , Adulto JovemAssuntos
Hidrocistoma/patologia , Hidrocistoma/cirurgia , Neoplasias das Glândulas Sudoríparas/patologia , Neoplasias das Glândulas Sudoríparas/cirurgia , Adenomas Tubulares de Glândulas Sudoríparas/patologia , Adenomas Tubulares de Glândulas Sudoríparas/cirurgia , Biópsia por Agulha , Sobrancelhas , Hidrocistoma/complicações , Humanos , Imuno-Histoquímica , Masculino , Prognóstico , Doenças Raras , Medição de Risco , Resultado do Tratamento , Adenomas Tubulares de Glândulas Sudoríparas/complicaçõesRESUMO
A 73-year-old Hispanic woman presented to the clinic with an erythematous, friable 3.0 cm × 2.7 cm × 0.7 cm mass located on the posterior vertex of the scalp (Figure 1). The lesion had been present since birth but had recently begun to bleed intermittently, prompting evaluation. A biopsy was obtained, revealing a tumor with irregular, complex papillomatous invaginations lined by a two-layered epithelium. Atypical and crowded columnar cells lined the luminal aspect, while cuboidal cells lined the epithelium adjacent to the stroma (Figure 2). Decapitation secretion was noted in several areas on the luminal surface.
Assuntos
Carcinoma/patologia , Couro Cabeludo , Neoplasias das Glândulas Sudoríparas/patologia , Adenomas Tubulares de Glândulas Sudoríparas/patologia , Adulto , Carcinoma/cirurgia , Feminino , Humanos , Neoplasias das Glândulas Sudoríparas/cirurgia , Adenomas Tubulares de Glândulas Sudoríparas/cirurgiaRESUMO
A major review of the literature of syringocystadenoma papilliferum's (SCAP's) presentation and management is presented. In addition, a case report of this unique diagnosis presenting as a corneal abrasion in a 66-year-old-male is included. This benign adnexal tumor of the apocrine glands is most commonly found in the face and neck. When found on the eyelids, these lesions are commonly misdiagnosed as basal cell carcinoma or cysts. Diagnosis is made based on histopathology. Treatment is complete excision of the lesion and this has a low recurrence rate. While predominantly benign, there have been cases of basal cell carcinoma development or other malignant transformations. Of the 26 reported cases of SCAP of the eyelids, none have caused a corneal abrasion. The authors present the only known presentation of eyelid SCAP, causing corneal abrasions, and provide a review of literature with discussion of clinical presentation, natural history, diagnosis, and treatment of this rare, eyelid lesion with potential for malignant transformation.
Assuntos
Neoplasias Palpebrais/patologia , Neoplasias das Glândulas Sudoríparas/patologia , Adenomas Tubulares de Glândulas Sudoríparas/patologia , Idoso , Diagnóstico Diferencial , Neoplasias Palpebrais/cirurgia , Humanos , Masculino , Procedimentos Cirúrgicos Oftalmológicos , Neoplasias das Glândulas Sudoríparas/cirurgia , Adenomas Tubulares de Glândulas Sudoríparas/cirurgiaRESUMO
Syringocystadenoma papilliferum and tubular apocrine adenoma are rare benign sweat gland tumors. Syringocystadenoma papilliferum occurs alone or in association with other tumors. Although it is rare, the association of tubular apocrine adenoma with syringocystadenoma papilliferum developing in a sebaceous nevus on the scalp is well documented. However, the co-existence of these two tumors without the background of a sebaceous nevus has not been frequently reported. Syringocystadenoma papilliferum and tubular apocrine adenoma may have a histopathological overlap, but a few cases of a syringocystadenoma papilliferum combined with a tubular apocrine adenoma have been reported. Herein we describe an unusual case of syringocystadenoma papilliferum co-existing with a tubular apocrine adenoma located on the back of a 14-year-old patient in the absence of a pre-existing sebaceous nevus.
Assuntos
Cistadenoma/patologia , Neoplasias Primárias Múltiplas/patologia , Neoplasias das Glândulas Sudoríparas/patologia , Siringoma/patologia , Adenomas Tubulares de Glândulas Sudoríparas/patologia , Adolescente , Diagnóstico Diferencial , Humanos , Masculino , Neoplasias Primárias Múltiplas/cirurgia , Neoplasias das Glândulas Sudoríparas/cirurgia , Adenomas Tubulares de Glândulas Sudoríparas/cirurgiaRESUMO
Abstract: Syringocystadenoma papilliferum and tubular apocrine adenoma are rare benign sweat gland tumors. Syringocystadenoma papilliferum occurs alone or in association with other tumors. Although it is rare, the association of tubular apocrine adenoma with syringocystadenoma papilliferum developing in a sebaceous nevus on the scalp is well documented. However, the co-existence of these two tumors without the background of a sebaceous nevus has not been frequently reported. Syringocystadenoma papilliferum and tubular apocrine adenoma may have a histopathological overlap, but a few cases of a syringocystadenoma papilliferum combined with a tubular apocrine adenoma have been reported. Herein we describe an unusual case of syringocystadenoma papilliferum co-existing with a tubular apocrine adenoma located on the back of a 14-year-old patient in the absence of a pre-existing sebaceous nevus.
Assuntos
Humanos , Masculino , Adolescente , Neoplasias das Glândulas Sudoríparas/patologia , Siringoma/patologia , Cistadenoma/patologia , Adenomas Tubulares de Glândulas Sudoríparas/patologia , Neoplasias Primárias Múltiplas/patologia , Neoplasias das Glândulas Sudoríparas/cirurgia , Diagnóstico Diferencial , Adenomas Tubulares de Glândulas Sudoríparas/cirurgia , Neoplasias Primárias Múltiplas/cirurgiaRESUMO
We present a unique case of syringocystadenoma with malignant transformation into syringocystadenocarcinoma papilliferum and coexisting trichoblastoma arising de novo in a scalp swelling of long duration in a 78-year-old woman. Syringocystadenocarcinoma papilliferum was described by the World Health Organization as an extremely rare malignant adnexal tumor of apocrine origin with varied histology with some cases reported in literature.